I would think that the experienced human driver will outperform GPS when it comes to selecting optimal routes and alternates at various times of day, dependent on moment-by-moment assessment of traffic conditions. That's just a gut feeling, no cite to back it up.
This test is legendary. There was an interesting study done on the brains of the drivers who pass it:
http://blogs.discovermagazine.com/notrocketscience/2011/12/0...