If the above is what you need there's not strong reasons not to use React or similar. But for most things that will lead to an interest in "Vanilla JSX" this line of thinking is premature optimization - the advantages of vdom are extant but enormously overstated. JSX has many other advantages.

It's also not even an either-or. I've worked on a codebase that did both: React was loaded for some views & others were served with a lightweight JSX renderer.