Homicide is more like a prequel - the source material is the same as The Wire but was developed a decade earlier.
WOTC is indeed a follow-up of sort (same author as The Wire, produced recently), but the real follow-up to The Wire (i.e. what David Simon did straight after, bringing with him a bunch of actors from The Wire) was the short-lived Treme.
There's also The Deuce more recently. I found it excellent, though the subject matter (sex work and early 70s/80s porn industry) probably will turn a lot of folks off.
It doesn't turn me off at all. These things are quite normal in many European countries.
The taboo thing about any sexual topic is very American. I never understood where that comes from. I always suspected it came from religion as I don't have any but American society seems to be more religion-centric. But here where most people aren't religious, things like sex work are pretty normal.
there´s
- We Own This City
and
- Homicide: Life on the Street