My phone could not handle it at all, it started dropping widgets after the slime (like subway surfers and hydraulic press disappeared) and then it started to lag before finally my whole phone became unresponsive for a couple minutes even after the tab was closed. On an iPhone 12 mini so not the newest but still a little surprising that it stopped so early in the game.
You need 2,000,000 stimulation points for the last item which wins the game. It sounds like a lot, but by that point you’ll be generating an insane amount of points per second and passive consumption is worth more than clicking. It does get overwhelming, at one point I had to mute the sound for a minute or two before resuming.
If you want to know what the last item is, rot13 the next paragraph (https://rot13.com/ is an easy way to do it):
Gur ynfg vgrz vf “tbvat gb gur bprna”. Gur tnzr jneaf lbh gurer vf ab tbvat onpx nsgre gung. Vg fjvgpurf gb n pnyzvat ivqrb bs jnirf ba gur ornpu, jvgu perqvgf.
I gave up when I bought auto hydraulic press.