Yes, because there are very few instances where you would genuinely need to know that information. If you are in one of those (hint: you are my primary care physician or romantic partner), I will offer it to you freely. I believe this even though my biological and expressed gender align.
There are plenty of characteristics that are rude to ask even when they are factual. Asking people their age is often rude, even though it's not something they can change. Nobody is offended by the fact that they are not 21 but they can definitely be offended if you point that out to them.
Please cite the transsexual oriented communities you are part of in which it isn't considered polite to ask people about their preferred pronoun, from which the male/female ratio can be inferred with high confidence. (she: male, he: female)