Hardly. Even for those limited few who can afford the extra cost, a business class seat only slightly insulates you from the worst part of any flight... other annoying passengers.
Don't have kids. That way you can avoid the holiday season for your vacation.
No lines at security and your fellow passengers are business travelers and old people.
A lot of domestic flights, business is more like economy plus. Trans-Atlantic I don't really have complaints although red-eyes are still disruptive. (I pretty much always do London as a day flight even though it means an ungodly early start.) I agree it's not a hotel room although I often don't sleep well the first night in a hotel room after an international flight either. AFAIK, there isn't anything even on the drawing board that could do trans-Pacific non-stop.