Arnim Ronacher, author of rye (later uv) has very clearly highlighted that exact xkcd when he started working on rye. But he still decided that it was worth a try and as it turns out, rye/uv has become something that has a realistic chance of becoming the way to use python for most use-cases.

Cool point, thank you. I think his name is Armin.

Thanks. You are right. Unfortunately I can't edit my post any longer.