I suspect SSRIs are prescribed because they are easy to prescribe.
I think they don't work because Depression, like Alzheimer's, is poorly defined.
From a population genetics perspective we can find clear genetic signals for other psychiatric disorders such as Schizophrenia, ADHD, etc. But Depression is notoriously difficult to identify any genetic signal for. Its my opinion that this is because Depression is more often a symptom of another psychiatric disorder and only rarely is the root cause just Depression itself.
Many folks with ADHD, Bipolar, or other "mild" disorders go undiagnosed and get the Depression label instead and this muddies the waters.
I think they don't work because Depression, like Alzheimer's, is poorly defined.
From a population genetics perspective we can find clear genetic signals for other psychiatric disorders such as Schizophrenia, ADHD, etc. But Depression is notoriously difficult to identify any genetic signal for. Its my opinion that this is because Depression is more often a symptom of another psychiatric disorder and only rarely is the root cause just Depression itself.
Many folks with ADHD, Bipolar, or other "mild" disorders go undiagnosed and get the Depression label instead and this muddies the waters.