As you go up the antes, the number of viable strategies decreases, until it narrows down to just one or two a number of antes quite a ways before the "end".
IIRC localthunk has said that he considers the normal "beat Ante 8" of Balatro to be the "real" Balatro and that the "beat all the higher antes" is mostly there to satisfy people who want it but it is not what he is optimizing for. In contrast to a lot of Roguelikes where "beating the game" is more "an offramp for those who want to call it a day but technically just the beginning of the 'real' experience". Both of which are fine goals, IMHO, but I think it helps to know that Balatro's additional antes are not designed to be in the latter category.
IIRC localthunk has said that he considers the normal "beat Ante 8" of Balatro to be the "real" Balatro and that the "beat all the higher antes" is mostly there to satisfy people who want it but it is not what he is optimizing for. In contrast to a lot of Roguelikes where "beating the game" is more "an offramp for those who want to call it a day but technically just the beginning of the 'real' experience". Both of which are fine goals, IMHO, but I think it helps to know that Balatro's additional antes are not designed to be in the latter category.