reply
Apart from that, any hardening in Fedora can be utilized inside a Fedora VM on Qubes. Qubes doesn't force you to use VMs with no isolation inside.
Two official examples of how one could benefit from Qubes:
https://www.qubes-os.org/news/2022/10/28/how-to-organize-you...
and
https://blog.invisiblethings.org/2011/03/13/partitioning-my-...
See also: https://forum.qubes-os.org/t/how-to-pitch-qubes-os/4499/15