pgflow can be used with any language/runtime, I just started with TypeScript and Supabase, as that's what I'm using.
The worker is stateless and "dumb" by design (currently it runs on serverless functions) - it just calls SQL functions: "poll_for_tasks" to get some tasks from the queue and then either "complete_task" or "fail_task" after executing user code - that's it, nothing more, so it should be relatively easy to adopt it to other runtimes.