You're not wrong, but the biggest confounding factor for LSD is that a 100ug dose comes embedded in 10000ug of blotter paper. Scales are useless for determining how much you're taking.
This is true of every illegal drug to some extent. You do not know how it is mixed.
Though sure, your 100mg of "MDMA" is unlikely to contain more than 100mg of MDMA
My point is that the potency at small doses creates novel hazards which, when avoided (and rightly so) interfere with the ability to know what you have.
One dose would be tricky, but you could process twenty doses of "MDMA" via column chromatography and end up with a sample of MDMA which your scale can actually measure. There's nothing scary about twenty doses of MDMA except that maybe you'll get caught with it. If you dropped it, nobody would get hurt.
If you tried the same with LSD you'd have to process tens of thousands of doses before your scale would be of any use. That much LSD in solution is an accident waiting to happen. I wouldn't go anywhere near it.
That is not true and dangerous. 20 doses is deadly. It's less than the LD50 for most people, but since MDMA disregulates your body temperature you can easily overheat
Well yeah, if you consume it. I'm worried about it splashing out and touching your hand. That's how LSD was discovered, Hoffman accidentally touched it and got a massive dose. I'm just saying that its much more dangerous to be near several grams of LSD than it is to be near several grams of MDMA, which means that the only person who can tell you the potency is likely the person who was crazy enough to make it in the first place.