You can't use animal models for dose, you have to convert to hED (Human-Equivalent Dosage). You can estimate this generally with allometric scaling:
https://drughunter.com/practical-pk-calculators
Also, animal physiology varies.
Beta-adrenergic agonists like clenbuterol make mice wildly muscular, which unfortunately is not the case in humans, for example.
You can't use animal models for dose, you have to convert to hED (Human-Equivalent Dosage). You can estimate this generally with allometric scaling:
https://drughunter.com/practical-pk-calculators
Also, animal physiology varies.
Beta-adrenergic agonists like clenbuterol make mice wildly muscular, which unfortunately is not the case in humans, for example.