Adblocking as links bloking can be sufficient, but sometimes you need to bring the big guns and alter the page content itself. Safari has even "Hide distracting elements" now, which can not be an extension. That cements the idea that most uBlock Origin features should be part of the browser to make it a wonderful user agent.
It's been possible to use Content Blockers for Safari for a long time, which alters the page content. Firefox Focus came out about a decade ago, and can be used as one.