I doubt it would come to completely replace LaTeX. The momentum behind LaTeX is enormous. Having said that, if it manages to simplify language handling, fonts, and bibliographhies it would be great.

But, especially, it would be good to see whether it improves on LaTeX's handling of tabulars (tables) and floats (figures), somethingh that is kind of an esoteric art right now. I wish Typst the best.