Most frameworks can serialize and deserialize JSON from strongly typed classes. For example, Newtonsoft in .NET. The rest isn't worth the effort for most people. Your scenario may be unusual.
I've certainly had some unusual contents in the past where we had approximately 10,000 configurable properties on the system, but we didn't use SQLite for that. Regardless, you ignored 3 of the 4 (I'll ignore the last one, it applies to JSON too) other points I made. My use cases aren't that weird and I'm not saying reach for SQLite every time, it's one option out of many. Migrations and runtime configuration change alone justify it for me in many cases.
