It's a trade off. The first place I worked mis-planned their moved, and was suffering the following 3.5 years to maintain profitability. The margins weren't high enough and through put did not increase enough to justify the more expensive location. I think they moved out of that location about 10 years later, when the employee base had shrunk to a quarter of the original size.

Yes, it is a single antidote, and there other complicating factors ... such as it being 2002 when the markets were already difficult.