> Standing to work has long known to be problematic, it is more tiring, it dramatically increases the risks of carotid atherosclerosis (ninefold) because of the additional load on the circulatory system, and it also increases the risks of varicose veins, so standing all day is unhealthy. The performance of many fine motor skills also is less good when people stand rather than sit.

> The key is to build movement variety into the normal workday.”

http://saveyourself.ca/articles/chair-warriorism.php

http://ergo.human.cornell.edu/CUESitStand.html