The btc-e API is far far worse. Some of the messages are in Russian and some are in English (randomly). Even worse (and a deal breaker for me) is that the order id can change underneath you if your transaction is split to fill the order, so there is no way to tell if your order completed or not. I've talked to people on Reddit who say they've made it work, but I'd never trust a bot spending money against an API like that. It's amateur hour when it comes to these exchanges and their API designs.
That's the same (almost) issue that Mt.Gox supposedly famously had with the actual blockchain, transaction malleability. I've read that Mt.Gox actually lost tens of Bitcoins in this way and it was a red herring for the whole actual giant scam that was perpetrated, but it was still a real vulnerability that needed patching or working around.
