That would be interesting if caffeine did affect the metabolism of alcohol. The points here are more about perception than any chemical mechanism as originally described:
>It very well not have been the algae but the reaction of the algae that occurred when another chemical's concentration was increase and caused a second or third order reaction.
I can't think of any chemical reactions like that off the top of my head. Some times different chemicals or the same chemical from different foods will reinforce each other.
Mixing Laxatives like prune juice and pineapples can have a stronger effect. Having two new foods that would both produce gas get's a significantly stronger reaction together. Excessive lean meat consumption can cause problems due to protein poisoning. There are also some poisons that act together.
