Before the VW diesel cheating scandal, it was alleged that US manufacturers were taking advantage of the EPA's test cycle procedure to "tune" ECM values when the dome light was active.
More than that, CAFE standards have become the ceiling for fuel economy rather than the envisioned floor. Manufacturers game the system by classifying certain cars as SUVs, claiming extra credit for the ability to run E85, or practically giving away efficient but undesirable vehicle configurations in order to just meet the target and avoid the gas guzzler tax.
IMO, the law ought to be "As soon as a measure becomes known it ceases to become a good measure."
"I'm fat because I can't touch my toes? Hang on, I'll be back in three weeks."
"What's that? Your measure for gas consumption and co2 emissions has you go exactly 35 MPH for 10 minutes? Hmm....."